Patient Profiles
Patient types that may be appropriate for ULTOMIRIS®

Meet Craig
A 35-year-old, newly diagnosed with anti-AChR antibody-positive gMG but already experiencing severe symptomsa
Age: 35 | Background: Delivery Driver | Length of Disease: 1 year | Location: California
Past medical history
- Unremarkable
History of present illness
- Craig was diagnosed with anti-AChR antibody-positive generalized myasthenia gravis (gMG) after a hospitalization for respiratory failure 3 months ago.
- Craig transitioned 4 weeks ago to outpatient care after being treated with IVIg inpatient for a gMG exacerbation.
Current medications
- Prednisone 80 mg once daily
- Azathioprine 150 mg once daily
- IVIg 2 g/kg (rescue therapy) during hospitalization
Chief complaint
- Craig has been experiencing severe, persistent limb muscle weakness and respiratory muscle weakness. Craig is unable to work due to his symptoms.

Meet Rex
A 52-year-old with persistent mild anti-AChR antibody-positive gMG symptomsa
Age: 52 | Background: Office Worker | Length of Disease: 2 years | Location: Rural Ohio
Past medical history
- Rex has type 2 diabetes, obesity, and anxiety.
History of present illness
- Rex has anti-AChR antibody-positive gMG, which has historically been treated with high-dose steroids for the past 2 years.
- Rex has failed 2 attempts to taper off steroids and experienced breakthrough symptoms.
Current medications
- Prednisone 80 mg once daily
- Azathioprine 200 mg once daily
- Pyridostigmine 60 mg three times daily
Chief complaint
- Persistent mild gMG symptoms, including increased fatigue while completing daily tasks and shortness of breath upon exertion.

Meet Linda
A 32-year-old patient with persistent anti-AChR antibody-positive gMG symptoms despite treatmenta
Age: 32 | Background: Working mother with an active 2 year old | Length of Disease: 18 months | Location: New Jersey
Past medical history
- Linda has no significant prior medical history, except for a diagnosis of anti-AChR antibody-positive gMG 18 months ago.
History of present illness
- Linda was diagnosed with anti-AChR antibody-positive gMG 18 months ago with persistent weakness in her extremities and is now experiencing breakthrough symptoms 12 months post-thymectomy.
Current medications
- Prednisone 20 mg once daily
- Pyridostigmine 60 mg four times daily
Previous medications
- Prednisone 40 mg once daily
Chief complaint
- Linda experiences intermittent slurring of speech, increased shortness of breath upon exertion, and lower limb paresis.
aPatient cases are fictitious and intended only for
discussion about patient experiences. Patient cases are not intended
for diagnosis or treatment purposes.
AChR, acetylcholine receptor; gMG, generalized myasthenia gravis;
IVIg, intravenous immunoglobulin; MG-ADL, Myasthenia Gravis
Activities of Daily Living; QMG, Quantitative Myasthenia Gravis.
ULTOMIRIS (ravulizumab‑cwvz) Efficacy
Find out the changes in MG-ADL and QMG total scores for patients in CHAMPION-MG.
View Efficacy Data